Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982789 | 0.86 | PTPN1 (0.35) | PTPN1ADORA2B | |
| SCHEMBL9039317 | 0.85 | — | — | |
| SCHEMBL9041754 | 0.85 | PTPN1 (0.34) | PTPN1MAOBADORA2B | |
| SCHEMBL9040322 | 0.82 | PTPN1 (0.35) | PTPN1ADORA2B | |
| SCHEMBL9041444 | 0.82 | PTPN1 (0.35) | PTPN1ADORA2B | |
| SCHEMBL9041335 | 0.81 | PTPN1 (0.37) | PTPN1GRM5 | |
| SCHEMBL6998066 | 0.81 | PTPN1 (0.33) | PTPN1ADORA2B | |
| SCHEMBL9040855 | 0.81 | PTPN1 (0.39) | PTPN1GRM5 | |
| SCHEMBL9041354 | 0.77 | L3MBTL1 (0.39) | GRM5 | |
| SCHEMBL6994951 | 0.73 | PTPN1 (0.36) | PTPN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441349-B1 | Pyrroloazepine derivatives | SUNTORY LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |