Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7943915 | 0.99 | HRH3 (0.44) | HRH3HTR1ASLC6A4SIGMAR1MAOB | |
| SCHEMBL6995202 | 0.87 | HRH3 (0.45) | HRH3SIGMAR1MAOB | |
| SCHEMBL7002079 | 0.87 | DRD2 (0.50) | HRH3 | |
| Hydrochloric Acid SCHEMBL7953973 | 0.87 | HRH3 (0.44) | HRH3SIGMAR1 | |
| SCHEMBL6991629 | 0.87 | HRH3 (0.51) | HRH3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL7952278 | 0.86 | DRD2 (0.49) | HRH3 | |
| Hydrochloric Acid SCHEMBL7943799 | 0.86 | HRH3 (0.50) | HRH3HTR1ASLC6A4 | |
| SCHEMBL6998550 | 0.82 | DRD2 (0.49) | HRH3HTR1ASLC6A4 | |
| SCHEMBL7000086 | 0.82 | DRD2 (0.52) | HTR1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7950663 | 0.82 | DRD2 (0.48) | HRH3HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023898-B1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1023898-A1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | ADIR ET COMPAGNIE (FR) | 2000-08-02 | — | — | EP | disclosed |