Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7950663 | 0.99 | DRD2 (0.48) | DRD2DRD3P2RX7PRMT5CCR3 | |
| SCHEMBL6994174 | 0.94 | DRD2 (0.51) | DRD2DRD3P2RX7PRMT5CCR3 | |
| Hydrochloric Acid SCHEMBL7952452 | 0.93 | DRD2 (0.50) | DRD2DRD3P2RX7PRMT5CCR3 | |
| SCHEMBL7002079 | 0.93 | DRD2 (0.50) | DRD2DRD3P2RX7PRMT5CCR3 | |
| Hydrochloric Acid SCHEMBL7952278 | 0.92 | DRD2 (0.49) | DRD2DRD3PRMT5CCR3HRH3 | |
| SCHEMBL6991633 | 0.90 | P2RX7 (0.47) | DRD2DRD3P2RX7PRMT5CCR3 | |
| Hydrochloric Acid SCHEMBL7950551 | 0.89 | P2RX7 (0.46) | DRD2DRD3P2RX7PRMT5HRH3 | |
| SCHEMBL7000086 | 0.87 | DRD2 (0.52) | DRD2DRD3P2RX7PRMT5CCR3 | |
| Hydrochloric Acid SCHEMBL7951962 | 0.86 | DRD2 (0.51) | DRD2DRD3P2RX7PRMT5CCR3 | |
| SCHEMBL6991629 | 0.84 | HRH3 (0.51) | DRD2DRD3PRMT5HRH3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023898-B1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1023898-A1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | ADIR ET COMPAGNIE (FR) | 2000-08-02 | — | — | EP | disclosed |