Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998399 | 1.00 | ABCB1 (0.46) | ABCB1SIGMAR1EBPTMEM97KDM4E | |
| SCHEMBL6998407 | 1.00 | ABCB1 (0.46) | ABCB1SIGMAR1EBPTMEM97KDM4E | |
| SCHEMBL6999326 | 0.95 | HTR1A (0.43) | SIGMAR1EBPTMEM97ALDH1A1 | |
| SCHEMBL6999331 | 0.95 | HTR1A (0.43) | SIGMAR1EBPTMEM97ALDH1A1 | |
| SCHEMBL6999335 | 0.95 | HTR1A (0.43) | SIGMAR1EBPTMEM97ALDH1A1 | |
| SCHEMBL6995341 | 0.89 | ACHE (0.48) | SIGMAR1 | |
| SCHEMBL6995337 | 0.89 | ACHE (0.48) | SIGMAR1 | |
| SCHEMBL6995343 | 0.89 | ACHE (0.48) | SIGMAR1 | |
| SCHEMBL7001096 | 0.86 | HTR2A (0.49) | TMEM97 | |
| SCHEMBL6998747 | 0.85 | DRD1 (0.43) | SIGMAR1EBPTMEM97ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |