Sugi Predict

Sugi Predict / Compounds / SCHEMBL6998428

SCHEMBL6998428

SCHEMBL6998428

CNC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.50
▸ BCHE P06276 2/20 0.50
▸ ACHE P22303 2/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ POLB P06746 1/20 0.50
▸ ATM Q13315 1/20 0.50
▸ GPR3 P46089 2/20 0.46
▸ LMNA P02545 1/20 0.44
▸ MAPT P10636 1/20 0.41
▸ HTR2A P28223 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ HDAC3 O15379 1/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ HDAC7 Q8WUI4 1/20 0.40
▸ HDAC8 Q9BY41 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ HDAC9 Q9UKV0 1/20 0.40
▸ HDAC5 Q9UQL6 1/20 0.40
▸ NCOR2 Q9Y618 1/20 0.40
▸ PPIA P62937 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3895431 0.97 KMT2A (0.48) KMT2ABCHEACHEMEN1POLB
SCHEMBL2001938 0.78 BCHE (0.61) KMT2ABCHEACHEMEN1POLB
SCHEMBL9834139 0.75 CYP2D6 (0.48) KMT2AMEN1LMNAHTR2APDPK1
SCHEMBL10209358 0.74 BCHE (0.47) KMT2ABCHEACHEMEN1POLB
SCHEMBL16361430 0.74 HDAC3 (0.50) KMT2ABCHEACHEMEN1POLB
SCHEMBL15494568 0.74 BCHE (0.47) KMT2ABCHEACHEMEN1POLB
SCHEMBL7003542 0.73 HTR2A (0.57) HTR2AHDAC4HDAC7HDAC5PDPK1
SCHEMBL7001558 0.73 SLC6A2 (0.39) KMT2ABCHEACHEMEN1POLB
SCHEMBL13676379 0.73 KMT2A (0.46) KMT2ABCHEACHEMEN1POLB
SCHEMBL28686639 0.73 KMT2A (0.46) KMT2ABCHEACHEMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936136-B Novel imidazopyrimidine compounds and uses thereof 儿童医学中心公司 2024-07-05 — — CN disclosed
EP-3672951-B1 QUINOXALINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2023-08-30 — — EP disclosed
WO-2023070987-A9 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2023-08-24 — — WO disclosed
EP-4198020-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2023-06-21 — — EP disclosed
WO-2023087557-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-05-25 — — WO disclosed
WO-2023070987-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2023-05-04 — — WO disclosed
WO-2022213794-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-10-13 — — WO disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 — — US disclosed
CN-105431424-B Compound, material for organic electroluminescent element, ink composition, organic electroluminescent element, electronic device, and method for producing organic electroluminescent element 出光兴产株式会社 2019-09-06 — — CN disclosed
US-9365614-B2 IAP BIR domain binding compounds PHARMASCIENCE INC. (CA) 2016-06-14 — — US disclosed
CN-101189229-A Synthesis of avrainvillamide, stephacidin B, and analogues thereof HARVARD COLLEGE (US) 2008-05-28 — — CN disclosed
US-7368528-B2 Antineoplastic peptides ABBOTT GMBH & CO. KG (DE) 2008-05-06 — — US disclosed
US-7368528-B2 Antineoplastic peptides ABBOTT GMBH & CO. KG (DE) 2008-05-06 — — US disclosed
US-20070043095-A1 Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use IPSEN PHARMA S.A.S. (FR) 2007-02-22 — — US disclosed
CN-1147489-C New bicyclo aminopyrazineone compound, its producing process and medical composition containing them ɪά��ʵ���� 2004-04-28 — — CN disclosed
EP-1069132-B1 Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them SERVIER LAB (FR) 2003-10-01 — — EP disclosed
EP-1069132-A1 Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them ADIR ET COMPAGNIE (FR) 2001-01-17 — — EP disclosed
CN-1277198-A New bicyclo aminopyrazineone compound, its producing process and medical composition containing them ADIR (FR) 2000-12-20 — — CN disclosed
EP-0628542-B1 Process for the preparation of organic carbamates BAYER AG (DE) 1997-04-09 — — EP disclosed
EP-0628542-A1 Process for the preparation of organic carbonates BAYER AG (DE) 1994-12-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 KMT2A 2769/4885BCHE 4171/4885ACHE 4325/4885
US-20070043095-A1 Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use SSTR2, SSTR5, SSTR3 KMT2A 3603/4885BCHE 2747/4885ACHE 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.