Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133396 | 0.73 | MAOA (0.41) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| SCHEMBL6998428 | 0.73 | KMT2A (0.50) | LMNATSHRBCHEACHEHTR2A | |
| SCHEMBL904813 | 0.73 | MAOA (0.41) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL3895431 | 0.71 | KMT2A (0.48) | LMNATSHRBCHEACHEHTR2A | |
| SCHEMBL3068122 | 0.70 | MAOA (0.38) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| SCHEMBL9834139 | 0.70 | CYP2D6 (0.48) | SLC6A2CYP2D6ADRA1AKCNH2LMNA | |
| SCHEMBL11834975 | 0.70 | CYP2D6 (0.59) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| SCHEMBL16835553 | 0.69 | HTR2C (0.46) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| SCHEMBL7400164 | 0.69 | HTR2C (0.39) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A | |
| SCHEMBL29697456 | 0.69 | MAOA (0.46) | SLC6A2CYP2D6ADRA2ASLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147489-C | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ɪά��ʵ���� | 2004-04-28 | — | — | CN | disclosed |
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |
| CN-1277198-A | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ADIR (FR) | 2000-12-20 | — | — | CN | disclosed |