Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.57 |
| ▸ | HRH1 | P35367 | 11/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998985 | 0.86 | PDPK1 (0.59) | HTR2AHRH1PDPK1HTR2C | |
| Hydrochloric Acid SCHEMBL6718185 | 0.84 | PDPK1 (0.57) | HTR2AHRH1PDPK1HTR2C | |
| SCHEMBL21259170 | 0.83 | PDPK1 (0.55) | HTR2AHRH1PDPK1 | |
| SCHEMBL21259158 | 0.81 | PDPK1 (0.44) | HTR2AHRH1PDPK1HTR2C | |
| SCHEMBL6997518 | 0.80 | HTR2A (0.44) | HTR2AHRH1PDPK1HTR2CHDAC4 | |
| SCHEMBL20749590 | 0.74 | PDPK1 (0.50) | HTR2AHRH1PDPK1HTR2C | |
| SCHEMBL6998428 | 0.73 | KMT2A (0.50) | HTR2APDPK1HDAC4HDAC7HDAC5 | |
| SCHEMBL9633656 | 0.73 | HTR2A (0.58) | HTR2AHRH1HTR2CHDAC4HDAC7 | |
| Dimethylamine SCHEMBL7194670 | 0.72 | DRD2 (0.52) | HTR2AHRH1PDPK1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3895431 | 0.71 | KMT2A (0.48) | HTR2AHDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147489-C | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ɪά��ʵ���� | 2004-04-28 | — | — | CN | disclosed |
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| CN-1277198-A | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ADIR (FR) | 2000-12-20 | — | — | CN | disclosed |