Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7950551 | 0.99 | P2RX7 (0.46) | P2RX7ACHEHRH3PRMT5DRD2 | |
| SCHEMBL6993372 | 0.93 | ALDH1A1 (0.48) | ACHEHRH3PRMT5DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7950497 | 0.92 | ALDH1A1 (0.47) | ACHEHRH3PRMT5DRD2DRD3 | |
| SCHEMBL6996474 | 0.91 | KDM4E (0.46) | P2RX7ACHEPRMT5CCR3 | |
| Hydrochloric Acid SCHEMBL7945151 | 0.90 | KDM4E (0.45) | P2RX7PRMT5CCR3 | |
| SCHEMBL6998550 | 0.90 | DRD2 (0.49) | P2RX7ACHEHRH3PRMT5DRD2 | |
| Hydrochloric Acid SCHEMBL7950663 | 0.89 | DRD2 (0.48) | P2RX7ACHEHRH3PRMT5DRD2 | |
| SCHEMBL6997268 | 0.88 | CXCR4 (0.45) | P2RX7PRMT5 | |
| SCHEMBL6994174 | 0.88 | DRD2 (0.51) | P2RX7PRMT5DRD2DRD3CCR3 | |
| Hydrochloric Acid SCHEMBL7945183 | 0.87 | CXCR4 (0.44) | P2RX7PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023898-B1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1023898-A1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | ADIR ET COMPAGNIE (FR) | 2000-08-02 | — | — | EP | disclosed |