Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998779 | 1.00 | KDM1A (0.55) | KDM1AMAOAMAOBSMN1; SMN2GAA | |
| SCHEMBL15212423 | 0.79 | KDM1A (0.60) | KDM1AMAOAMAOBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7093973 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7093972 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBSMN1; SMN2GAA | |
| SCHEMBL6993703 | 0.77 | KDM1A (0.57) | KDM1AMAOAMAOBKDM4EMAPT | |
| SCHEMBL6993699 | 0.77 | KDM1A (0.57) | KDM1AMAOAMAOBKDM4EMAPT | |
| SCHEMBL7629070 | 0.76 | SMN1; SMN2 (0.80) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL7096726 | 0.72 | MAOA (0.42) | KDM1AMAOAMAOBSMN1; SMN2GAA | |
| SCHEMBL7096728 | 0.72 | MAOA (0.42) | KDM1AMAOAMAOBSMN1; SMN2GAA | |
| SCHEMBL687206 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056749-B1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2003-02-19 | — | — | EP | disclosed |
| US-6369064-B1 | MYOCARDIAL INFARCTION AND UNSTABLE ANGINA; P2T-RECEPTOR ANTAGONISTS; ANTITHROMBOTIC AGENTS; 7-(SUBSTITUTED AMINO) -5-(THIO)-3H-1,2,3-TRIAZOLO(4,5-D)PYRIMIDIN-3-YL) -CYCLOPENTANECARBOXAMIDES | ASTRAZENECA AB (SE) | 2002-04-09 | — | — | US | disclosed |