Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096728 | 1.00 | MAOA (0.42) | MAOAKDM1ASMN1; SMN2GAACA12 | |
| SCHEMBL7096959 | 0.83 | CHRNA7 (0.49) | MAOAKDM1ACA12CA1CA2 | |
| SCHEMBL7096961 | 0.83 | CHRNA7 (0.49) | MAOAKDM1ACA12CA1CA2 | |
| SCHEMBL7006389 | 0.81 | MAOA (0.37) | MAOAKDM1AGAACA12CA1 | |
| SCHEMBL7002740 | 0.76 | MAOA (0.51) | MAOAKDM1ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6753602 | 0.74 | KDM1A (0.49) | MAOAKDM1ALMNAHTTALDH1A1 | |
| SCHEMBL7003744 | 0.74 | DRD2 (0.42) | GAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL6753603 | 0.74 | KDM1A (0.49) | MAOAKDM1ALMNAHTTALDH1A1 | |
| SCHEMBL6998779 | 0.72 | KDM1A (0.55) | MAOAKDM1ASMN1; SMN2GAACA12 | |
| SCHEMBL6998780 | 0.72 | KDM1A (0.55) | MAOAKDM1ASMN1; SMN2GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097153-B1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |