Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.56 |
| ▸ | THRA | P10827 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995423 | 0.87 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL13949758 | 0.86 | THRB (0.58) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL1526069 | 0.82 | THRB (0.59) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL8417806 | 0.82 | THRB (0.59) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL10780803 | 0.82 | THRB (0.59) | THRBTHRAPPARGMEN1KMT2A | |
| Acetic Acid SCHEMBL9042977 | 0.82 | THRB (0.72) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL6999917 | 0.81 | THRB (0.71) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL6996521 | 0.81 | THRB (0.44) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL14509288 | 0.80 | THRB (0.54) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL12808939 | 0.80 | THRB (0.56) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648272-A | Reagents and methods for the detection and quantification of thyroxine in fluid samples | ABBOTT LABORATORIES (US) | 1997-07-15 | — | — | US | claimed |
| EP-0649533-A4 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES. | ABBOTT LAB (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0649533-A1 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES | ABBOTT LABORATORIES (US) | 1995-04-26 | — | — | EP | claimed |
| WO-1993020442-A1 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES | ABBOTT LABORATORIES (US) | 1993-10-14 | — | — | WO | claimed |
| EP-0959355-B1 | Reagents for the detection and quantification of thryoxine in fluid samples | ABBOTT LAB (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0649533-B1 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES | ABBOTT LAB (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0959355-A1 | Reagents for the detection and quantification of thryoxine in fluid samples | ABBOTT LABORATORIES (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5691456-A | IMMUNOGENS CONTAINING BOVINE SERUM ALBUMIN AND FLUORESCEIN COMPOUND | ABBOTT LABORATORIES (US) | 1997-11-25 | — | — | US | disclosed |
| US-5688921-A | IMMUNOGENS CONTAINING BOVINE SERUM ALBUMIN AND FLUORESCEIN COMPOUND | ABBOTT LABORATORIES D-337/AP6D (US) | 1997-11-18 | — | — | US | disclosed |
| US-5648272-A | Reagents and methods for the detection and quantification of thyroxine in fluid samples | ABBOTT LABORATORIES (US) | 1997-07-15 | — | — | US | disclosed |
| US-5593896-A | COMPETITIVE IMMUNOASSAY | ABBOTT LABORATORIES (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0649533-A4 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES. | ABBOTT LAB (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0649533-A1 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES | ABBOTT LABORATORIES (US) | 1995-04-26 | — | — | EP | disclosed |
| US-5359093-A | For sensitive immunoassays | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993020442-A1 | REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES | ABBOTT LABORATORIES (US) | 1993-10-14 | — | — | WO | disclosed |