SCHEMBL6999917

SCHEMBL6999917

CC(C)(C)OC(=O)[C@@H](N)Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 11/20 0.71
▸ MEN1 O00255 7/20 0.71
▸ KMT2A Q03164 7/20 0.71
▸ THRA P10827 7/20 0.71
▸ LMNA P02545 5/20 0.71
▸ PPARG P37231 5/20 0.71
▸ USP2 O75604 4/20 0.71
▸ HSD17B10 Q99714 3/20 0.71
▸ TTR P02766 2/20 0.71
▸ ADORA3 P0DMS8 2/20 0.71
▸ PDE4D Q08499 2/20 0.71
▸ RXRA P19793 2/20 0.71
▸ ALDH1A1 P00352 2/20 0.71
▸ MAPT P10636 2/20 0.71
▸ NR1I2 O75469 2/20 0.71
▸ NR3C1 P04150 1/20 0.71
▸ CYP1A2 P05177 1/20 0.71
▸ HTR1A P08908 1/20 0.71
▸ CYP2C9 P11712 1/20 0.71
▸ TBXA2R P21731 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9042977 0.98 THRB (0.72) THRBMEN1KMT2ATHRALMNA
SCHEMBL7258345 0.90 SIRT5 (0.54) THRBMEN1KMT2ATHRALMNA
SCHEMBL17182783 0.90 SIRT5 (0.54) THRBMEN1KMT2ATHRALMNA
SCHEMBL4310917 0.86 THRB (0.76) THRBMEN1KMT2ATHRALMNA
SCHEMBL8369339 0.86 THRB (0.76) THRBMEN1KMT2ATHRALMNA
SCHEMBL8369341 0.86 THRB (0.76) THRBMEN1KMT2ATHRALMNA
SCHEMBL9748040 0.85 THRB (0.74) THRBMEN1KMT2ATHRALMNA
Hydrochloric Acid SCHEMBL8825443 0.85 THRB (0.74) THRBMEN1KMT2ATHRALMNA
SCHEMBL9746882 0.85 THRB (0.74) THRBMEN1KMT2ATHRALMNA
Hydrochloric Acid SCHEMBL8825447 0.85 THRB (0.74) THRBMEN1KMT2ATHRALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0959355-B1 Reagents for the detection and quantification of thryoxine in fluid samples ABBOTT LAB (US) 2003-05-14 — — EP disclosed
EP-0649533-B1 REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES ABBOTT LAB (US) 2000-05-10 — — EP disclosed
EP-0959355-A1 Reagents for the detection and quantification of thryoxine in fluid samples ABBOTT LABORATORIES (US) 1999-11-24 — — EP disclosed
US-5691456-A IMMUNOGENS CONTAINING BOVINE SERUM ALBUMIN AND FLUORESCEIN COMPOUND ABBOTT LABORATORIES (US) 1997-11-25 — — US disclosed
US-5688921-A IMMUNOGENS CONTAINING BOVINE SERUM ALBUMIN AND FLUORESCEIN COMPOUND ABBOTT LABORATORIES D-337/AP6D (US) 1997-11-18 — — US disclosed
US-5648272-A Reagents and methods for the detection and quantification of thyroxine in fluid samples ABBOTT LABORATORIES (US) 1997-07-15 — — US disclosed
US-5593896-A COMPETITIVE IMMUNOASSAY ABBOTT LABORATORIES (US) 1997-01-14 — — US disclosed
US-5359093-A For sensitive immunoassays ABBOTT LABORATORIES (US) 1994-10-25 — — US disclosed
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