SCHEMBL6998988

SCHEMBL6998988

Cc1ccc2c(c1)C(C)(C)C(C)C2C(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29980582 1.00 CCR2 (0.32) CCR2
SCHEMBL9157274 0.86 HTR2A (0.30)
SCHEMBL9153517 0.79
SCHEMBL3169625 0.78 HTR2C (0.35) CCR2
SCHEMBL11278196 0.77 HTR2A (0.35)
SCHEMBL11272531 0.75 ABCB11 (0.37)
SCHEMBL11218949 0.75 HTR2C (0.33) CCR2
SCHEMBL11218952 0.75 HTR2C (0.33) CCR2
SCHEMBL11271994 0.73 HTR2C (0.32)
SCHEMBL4454523 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561447-B1 Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT QUEST INT (NL) 1997-01-02 EP claimed
US-5430015-A Acylation of tetralins UNILEVER PATENT HOLDINGS, BV (NL) 1995-07-04 US claimed
EP-0561447-A1 Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT QUEST INTERNATIONAL B.V. (NL) 1993-09-22 EP claimed
EP-1268733-A1 LAUNDRY TREATMENT FOR FABRICS UNILEVER PLC (GB) 2003-01-02 EP disclosed
WO-2001072944-A1 LAUNDRY TREATMENT FOR FABRICS UNILEVER PLC (GB) 2001-10-04 WO disclosed
EP-0561447-B1 Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT QUEST INT (NL) 1997-01-02 EP disclosed
US-5430015-A Acylation of tetralins UNILEVER PATENT HOLDINGS, BV (NL) 1995-07-04 US disclosed
WO-1995000113-A1 NOVEL FORMATE ESTER INDANE COMPOUNDS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5292720-A Formate ester indane compounds UNION CAMP CORPORATION (US) 1994-03-08 US disclosed
EP-0561447-A1 Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT QUEST INTERNATIONAL B.V. (NL) 1993-09-22 EP disclosed
US-4634548-A PERFUMES, FLAVORS GIVAUDAN CORPORATION (US) 1987-01-06 US disclosed
EP-0115274-B1 EPOXIDES OF BICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PERFUMED AND/OR FLAVOURED COMPOSITIONS CONTAINING THEM L. GIVAUDAN & CIE Société Anonyme (CH) 1986-11-05 EP disclosed
EP-0089207-B1 FRIEDEL-CRAFT REACTIONS BUSH BOAKE ALLEN Limited (GB) 1986-09-10 EP disclosed
US-4515990-A Preparation of indanes, tetralins and phenyl alcohol in Friedel Craft reaction BUSH BOAKE ALLEN LIMITED (GB) 1985-05-07 US disclosed
EP-0104195-A1 FRIEDEL CRAFT REACTIONS BUSH BOAKE ALLEN Limited (GB) 1984-04-04 EP disclosed
WO-1983003247-A1 FRIEDEL CRAFT REACTIONS FERBER, GERALD, JOHN 1983-09-29 WO disclosed
EP-0089207-A1 Friedel-Craft reactions BUSH BOAKE ALLEN Limited (GB) 1983-09-21 EP disclosed
US-4352748-A Novel acyl-polyalkylindan compounds and the use thereof as a base for perfume, as well as perfume compositions NAARDEN INTERNATIONAL N.V. (NL) 1982-10-05 US disclosed