Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218949 | 1.00 | HTR2C (0.33) | HTR2CCCR2THRBTDP1TP53 | |
| SCHEMBL3169625 | 0.89 | HTR2C (0.35) | HTR2CCCR2THRBTDP1TP53 | |
| SCHEMBL6998988 | 0.75 | CCR2 (0.32) | CCR2 | |
| SCHEMBL11265239 | 0.75 | — | — | |
| SCHEMBL29980582 | 0.75 | CCR2 (0.32) | CCR2 | |
| SCHEMBL5401924 | 0.74 | THRB (0.36) | CCR2THRBTDP1TP53CYP3A4 | |
| SCHEMBL5401929 | 0.74 | THRB (0.36) | CCR2THRBTDP1TP53CYP3A4 | |
| SCHEMBL5401919 | 0.74 | THRB (0.36) | CCR2THRBTDP1TP53CYP3A4 | |
| SCHEMBL13783235 | 0.67 | CCR2 (0.30) | CCR2 | |
| SCHEMBL1468020 | 0.66 | RXRA (0.39) | CCR2THRBTDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071006-A2 | Tetrahydronaphthalene derivatives and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-02-09 | — | — | EP | disclosed |