Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520014 | 0.82 | CYP3A4 (0.64) | MAOBROCK2ROCK1HDAC1CYP3A4 | |
| SCHEMBL7000383 | 0.80 | LTB4R (0.68) | LTB4RLTB4R2 | |
| SCHEMBL1059845 | 0.79 | MAOB (0.66) | MAOBHDAC1CYP3A4MAPTMEN1 | |
| SCHEMBL8462129 | 0.78 | MAOB (0.46) | MAOBROCK2ROCK1HDAC1CYP3A4 | |
| SCHEMBL8785126 | 0.76 | MAOB (0.57) | MAOBLTB4RLTB4R2HDAC1CYP3A4 | |
| SCHEMBL8335213 | 0.76 | ROCK2 (0.46) | ROCK2ROCK1TNIKPDK2EGFR | |
| SCHEMBL8785628 | 0.75 | MAOB (0.56) | MAOBLTB4RLTB4R2HDAC1CYP3A4 | |
| SCHEMBL8466024 | 0.72 | MAOB (0.54) | MAOBLTB4RLTB4R2HDAC1CYP3A4 | |
| SCHEMBL29478296 | 0.72 | MAOB (1.00) | MAOBLTB4RLTB4R2HDAC1CYP3A4 | |
| SCHEMBL2400347 | 0.72 | MAOB (1.00) | MAOBLTB4RLTB4R2HDAC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270000-A2 | Benzoic acid substituted benzopyrans for the treatment of atherosclerosis | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | disclosed |