Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.63 |
| ▸ | HTR2B | P41595 | 10/20 | 0.63 |
| ▸ | HTR2A | P28223 | 10/20 | 0.63 |
| ▸ | HTR1A | P08908 | 7/20 | 0.63 |
| ▸ | HTR1D | P28221 | 6/20 | 0.63 |
| ▸ | HTR6 | P50406 | 3/20 | 0.63 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.63 |
| ▸ | HTR1B | P28222 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002281 | 1.00 | HTR2C (0.63) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6996518 | 0.99 | HTR2C (0.62) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6094978 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5936562 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6092065 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL30390274 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6092175 | 0.77 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6205030 | 0.77 | HTR2C (0.50) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6093427 | 0.77 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6095848 | 0.77 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268482-A1 | PYRANOINDOLES FOR TREATING GLAUCOMA | Alcon Universal, Ltd. (CH) | 2003-01-02 | — | — | EP | claimed |
| WO-2001070745-A1 | PYRANOINDOLES FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2001-09-27 | — | — | WO | claimed |