Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328735 | 0.86 | RAPGEF4 (0.67) | RAPGEF4GAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL5608725 | 0.85 | NPSR1 (0.59) | RAPGEF4NPSR1GAAMAPTAKR1C3 | |
| SCHEMBL7003152 | 0.84 | GAA (0.60) | RAPGEF4GAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL44754 | 0.82 | NPSR1 (0.55) | RAPGEF4NPSR1GAAMAPTHSD17B10 | |
| SCHEMBL7003046 | 0.80 | GAA (0.53) | RAPGEF4GAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL7003454 | 0.80 | RAPGEF4 (0.60) | RAPGEF4NPSR1GAAMAPTALDH1A1 | |
| SCHEMBL22887353 | 0.80 | CDC25B (0.58) | AKR1C3AKR1C2TRPV1 | |
| SCHEMBL7003942 | 0.80 | RAPGEF4 (0.64) | RAPGEF4GAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL7644039 | 0.79 | GAA (0.61) | RAPGEF4GAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL11235317 | 0.78 | NPSR1 (0.70) | RAPGEF4NPSR1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566302-B1 | For use in heat sensitive and pressure sensitive recording materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-20 | — | — | US | disclosed |
| EP-1107972-B1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | CIBA SC HOLDING AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| EP-1115579-B1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SC HOLDING AG (CH) | 2002-11-20 | — | — | EP | disclosed |
| EP-1115579-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Ciba SC Holding AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000026037-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012318-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| EP-0546577-B1 | Crystal modification of 2-(3-methylanilino)-3-methyl-6-diethylaminofluoran, process for the preparation thereof, and recording materials containing said crystal modification | YAMAMOTO CHEMICALS INC (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5376617-A | Heat sensitive, pressure sensitive recording material | YAMAMOTO CHEMICALS, INC. (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5338866-A | Reacting 2-(2-hydroxy-4-diethylaminobenzoyl)benzoic acid with 2,3'-dimethyl-4-alkoxydiphenylamine in presence of condensing/ dehydrating agent | YAMAMOTO CHEMICALS, INC. (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0546577-A1 | Crystal modification of 2-(3-methylanilino)-3-methyl-6-diethylaminofluoran, process for the preparation thereof, and recording materials containing said crystal modification | Yamamoto Chemicals, Inc. (JP) | 1993-06-16 | — | — | EP | disclosed |