Sugi Predict

Sugi Predict / Compounds / SCHEMBL44754

SCHEMBL44754

SCHEMBL44754

Cc1cccc(Nc2ccc(-c3ccc(Nc4cccc(C)c4)c(C)c3)cc2C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 1/20 0.55
▸ AKR1C3 P42330 2/20 0.47
▸ AKR1C2 P52895 2/20 0.47
▸ MAPT P10636 4/20 0.46
▸ HTT P42858 3/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ NFKB1 P19838 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ RAPGEF4 Q8WZA2 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ SRC P12931 1/20 0.43
▸ PTGS1 P23219 1/20 0.42
▸ PTGS2 P35354 1/20 0.42
▸ BRD4 O60885 1/20 0.42
▸ KAT2B Q92831 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608725 0.89 NPSR1 (0.59) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL31508469 0.85 NPSR1 (0.44) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL4969457 0.84 NPSR1 (0.41) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL7001007 0.82 RAPGEF4 (0.53) NPSR1AKR1C3AKR1C2MAPTNFKB1
SCHEMBL3690304 0.81 NPSR1 (0.64) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL7003883 0.80 GAA (0.73) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL29066347 0.80 NPSR1 (0.58) NPSR1AKR1C3AKR1C2MAPTHTT
SCHEMBL24685150 0.79 GAA (0.59) NPSR1MAPTHTTCYP1A2CYP2D6
SCHEMBL7618672 0.79 RAPGEF4 (0.50) AKR1C3AKR1C2MAPTGAARAPGEF4
SCHEMBL8966403 0.78 NPSR1 (0.47) NPSR1AKR1C3AKR1C2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1374641-B1 DOUBLE DOPED-LAYER, PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES UNIV PRINCETON (US) 2017-12-27 — — EP claimed
US-9023490-B2 Extended pi-conjugated platinum (II) complexes VERSITECH LIMITED (CN) 2015-05-05 — — US claimed
US-8609258-B2 Light emitting devices and compositions NITTO DENKO CORPORATION (JP) 2013-12-17 — — US claimed
US-8597803-B2 Light emitting devices and compositions NITTO DENKO CORPORATION (JP) 2013-12-03 — — US claimed
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-12-06 — — US claimed
US-20120273765-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-11-01 — — US claimed
US-8003008-B1 Color-tailored polymer light emitting diodes including emissive colloidal particles and method of forming same CLEMSON UNIVERSITY (US) 2011-08-23 — — US claimed
US-20090179552-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-07-16 — — US claimed
WO-2009064661-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-05-22 — — WO claimed
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-03-12 — — US claimed
WO-2009006550-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-01-08 — — WO claimed
US-20080309227-A1 EXTENDED PI-CONJUGATED PLATINUM (II) COMPLEXES VERSITECH LIMITED (CN) 2008-12-18 — — US claimed
EP-1374641-A4 DOUBLE DOPED-LAYER, PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES UNIV PRINCETON (US) 2007-04-18 — — EP claimed
US-6867538-B2 Double doped-layer, phosphorescent organic light emitting devices THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2005-03-15 — — US claimed
EP-1374641-A1 DOUBLE DOPED-LAYER, PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2004-01-02 — — EP claimed
US-20020180347-A1 Double doped-layer, phosphorescent organic light emitting devices AIR FORCE, UNITED STATES 2002-12-05 — — US claimed
WO-2002071813-A1 DOUBLE DOPED-LAYER, PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-09-12 — — WO claimed
US-12043778-B2 Method for producing quantum dot composition and method for manufacturing light emitting element including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-23 — — US disclosed
WO-2002071813-A1 DOUBLE DOPED-LAYER, PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-09-12 — — WO disclosed
WO-2001093642-A1 PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2001-12-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS MAP1LC3A, MAP1LC3C, CRY1 NPSR1 4622/4885AKR1C3 3756/4885AKR1C2 3890/4885
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS ILK, CRY1, IK NPSR1 3794/4885AKR1C3 2091/4885AKR1C2 2403/4885
US-20090179552-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS CYBA, LIMA1, CRY1 NPSR1 3997/4885AKR1C3 3300/4885AKR1C2 3697/4885
US-20120273765-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS CYBA, LIMA1, CRY1 NPSR1 3997/4885AKR1C3 3300/4885AKR1C2 3697/4885
US-20080309227-A1 EXTENDED PI-CONJUGATED PLATINUM (II) COMPLEXES LIG4, PARG, PARN NPSR1 4096/4885AKR1C3 4224/4885AKR1C2 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.