Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703349 | 0.75 | KMT2A (0.45) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL7001248 | 0.72 | — | — | |
| SCHEMBL7618292 | 0.71 | PTGS2 (0.42) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL8649025 | 0.68 | PTGS2 (0.42) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL28224266 | 0.68 | CYP19A1 (0.55) | ALDH1A1KDM4EGLAMAPTHPGD | |
| SCHEMBL8708120 | 0.68 | PTGS2 (0.46) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL22022951 | 0.67 | PTGS2 (0.37) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL6999022 | 0.67 | PTGS2 (0.41) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL6993536 | 0.66 | SIGMAR1 (0.49) | PTGS2ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10300271 | 0.66 | ALDH1A1 (0.50) | PTGS2ALDH1A1NISCHPTGS1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |