Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003112 | 0.83 | ALDH1A1 (0.35) | TERTMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL7004266 | 0.83 | TERT (0.46) | TERTMEN1KMT2ACHRM2CYP1A2 | |
| SCHEMBL10066168 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL23954161 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL13340735 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL7008226 | 0.73 | CHKA (0.48) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13340756 | 0.73 | HTT (0.40) | POLBALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL23954383 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL13340749 | 0.69 | MAPT (0.37) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12391805 | 0.68 | CDC25A (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185531-B1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | WELLA AG (DE) | 2003-10-29 | — | — | EP | claimed |