Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066168 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1POLBGAA | |
| SCHEMBL7001391 | 0.83 | TERT (0.42) | ALDH1A1MAPTMEN1POLBGAA | |
| SCHEMBL7004036 | 0.80 | LCK (0.42) | MAPTMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL22432734 | 0.79 | TSHR (0.36) | ALDH1A1MAPTKMT2AHDAC1TSHR | |
| SCHEMBL23954161 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1GAARECQL | |
| SCHEMBL13340735 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1POLBGAA | |
| SCHEMBL7008226 | 0.75 | CHKA (0.48) | ALDH1A1MAPTSMN1; SMN2MAOBLMNA | |
| SCHEMBL13340756 | 0.75 | HTT (0.40) | ALDH1A1MAPTPOLBGAAMCL1 | |
| SCHEMBL23954383 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1POLBGAA | |
| SCHEMBL13340749 | 0.71 | MAPT (0.37) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185531-B1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | WELLA AG (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6570019-B2 | Hair dyes; uniformity, stability | WELLA AG (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20030055268-A1 | Cationic pyrrolo-pyrrol-derivatives, method for producing them and colorants for keratin fibres, containing these compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-03-20 | — | — | US | disclosed |
| EP-1185531-A1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001062759-A1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055268-A1 | Cationic pyrrolo-pyrrol-derivatives, method for producing them and colorants for keratin fibres, containing these compounds | KRT18, IK, PYCR1 | ALDH1A1 1647/4885MAPT 2160/4885MEN1 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.