SCHEMBL7001783

SCHEMBL7001783

COc1ccc(N)c(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
ALDH1A1 P00352 4/20 0.46
GAA P10253 2/20 0.46
EP300 Q09472 1/20 0.46
KAT8 Q9H7Z6 1/20 0.46
LTA4H P09960 1/20 0.44
ADRA2B P18089 1/20 0.44
PTGS1 P23219 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
POLB P06746 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42
MEN1 O00255 1/20 0.40
FGB P02675 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
ADORA2A P29274 1/20 0.40
PPARG P37231 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6069384 0.88 IDO1 (0.46) IDO1ALDH1A1GAAEP300KAT8
SCHEMBL6475571 0.88 IDO1 (0.46) IDO1ALDH1A1GAAEP300KAT8
SCHEMBL27640492 0.87 CALM1 (0.42) IDO1ALDH1A1GAALTA4HPOLB
SCHEMBL27984159 0.86 ALDH1A1 (0.53) ALDH1A1GAALTA4HADRA2BPTGS1
SCHEMBL1498780 0.82 CALM1 (0.55) ALDH1A1GAAPOLBMEN1MAPT
Alcohol SCHEMBL28228430 0.81 ALDH1A1 (0.48) ALDH1A1LTA4HADRA2BPTGS1TDP1
SCHEMBL17501675 0.81 ALDH1A1 (0.49) IDO1ALDH1A1GAAPOLBKDM4E
SCHEMBL28261794 0.79 LTA4H (0.42) LTA4HPOLBSMN1; SMN2
SCHEMBL3728677 0.79 LTA4H (0.52) ALDH1A1GAALTA4HTDP1POLB
SCHEMBL28195926 0.79 LTA4H (0.44) ALDH1A1GAALTA4HPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635602-B1 Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-21 US disclosed
EP-1107972-B1 PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN CIBA SC HOLDING AG (CH) 2003-01-02 EP disclosed