Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955652 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TDP1EPHX2KDM4E | |
| SCHEMBL6171439 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1EPHX2 | |
| SCHEMBL11556980 | 0.71 | KMT2A (0.58) | ALDH1A1SMN1; SMN2TDP1EPHX2NPC1 | |
| SCHEMBL230405 | 0.71 | NPC1 (0.71) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL518416 | 0.70 | KMT2A (0.69) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| Bromide SCHEMBL7247705 | 0.70 | NPC1 (0.69) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL18930812 | 0.69 | HSD17B1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8669485 | 0.69 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL20767198 | 0.68 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2EPHX2KMT2AMEN1 | |
| SCHEMBL5315078 | 0.68 | CES2 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340750-A1 | AMIDE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |