Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001447 | 0.93 | TSPO (0.62) | TSPOPOLBMAPTTP53KDM4E | |
| SCHEMBL5702445 | 0.91 | TSPO (0.67) | TSPOPOLBMAPTTP53 | |
| SCHEMBL7003506 | 0.90 | TSPO (0.59) | TSPOPOLBMAPTTP53 | |
| SCHEMBL7002472 | 0.87 | TSPO (0.56) | TSPOPOLBMAPTTP53KDM4E | |
| SCHEMBL7632526 | 0.87 | TSPO (0.54) | TSPOPOLBMAPTTP53ALDH1A1 | |
| SCHEMBL7498096 | 0.84 | TSPO (0.56) | TSPOPOLBMAPTTP53KDM4E | |
| SCHEMBL7626011 | 0.82 | TSPO (0.64) | TSPOMAPTTP53 | |
| SCHEMBL17959423 | 0.82 | TSPO (0.83) | TSPOPOLBMAT2A | |
| SCHEMBL7003823 | 0.81 | TSPO (0.71) | TSPOPOLBMAPTTP53KDM4E | |
| SCHEMBL5785794 | 0.80 | POLB (0.46) | TSPOPOLBMAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149101-B1 | 4-OXO-3,5-DIHYDRO-4$i(H)-PYRIDAZINO 4,5-$i(b)]INDOLE-1-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI SYNTHELABO (FR) | 2003-04-09 | — | — | EP | disclosed |