Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702445 | 0.96 | TSPO (0.67) | TSPOMAPTTP53POLB | |
| SCHEMBL7001998 | 0.93 | TSPO (0.57) | TSPOKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL7002472 | 0.92 | TSPO (0.56) | TSPOKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL7626011 | 0.89 | TSPO (0.64) | TSPOMAPTTP53 | |
| SCHEMBL7498096 | 0.87 | TSPO (0.56) | TSPOKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL6999958 | 0.86 | TSPO (0.54) | TSPOKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL7626419 | 0.86 | TSPO (0.58) | TSPOALDH1A1MAPTTP53 | |
| SCHEMBL7003823 | 0.85 | TSPO (0.71) | TSPOKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL6703839 | 0.85 | SMN1; SMN2 (0.54) | TSPOALDH1A1MAPTTP53POLB | |
| SCHEMBL7631555 | 0.83 | TSPO (0.65) | TSPOKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149101-B1 | 4-OXO-3,5-DIHYDRO-4$i(H)-PYRIDAZINO 4,5-$i(b)]INDOLE-1-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI SYNTHELABO (FR) | 2003-04-09 | — | — | EP | disclosed |