Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986605 | 0.81 | PDPK1 (0.48) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL3323928 | 0.81 | CES1 (0.52) | LMNAMAPTHPGDHTTMAPK1 | |
| SCHEMBL3319973 | 0.81 | CES1 (0.52) | LMNAMAPTHPGDHTTMAPK1 | |
| SCHEMBL3319972 | 0.81 | CES1 (0.52) | LMNAMAPTHPGDHTTMAPK1 | |
| SCHEMBL10846565 | 0.79 | PDPK1 (0.57) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL28376164 | 0.79 | LMNA (0.56) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL11990926 | 0.76 | SLC6A2 (0.55) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL27937876 | 0.76 | LMNA (0.45) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL9502922 | 0.76 | PDPK1 (0.63) | PDPK1LMNAMAPTESR1ESR2 | |
| SCHEMBL5144207 | 0.75 | LMNA (0.44) | PDPK1LMNAMAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270000-A2 | Benzoic acid substituted benzopyrans for the treatment of atherosclerosis | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | disclosed |