Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002681 | 0.81 | PDPK1 (0.52) | PDPK1BLMKDM4EALDH1A1ABL1 | |
| SCHEMBL28376164 | 0.81 | LMNA (0.56) | PDPK1ALDH1A1TDP1LMNAESR1 | |
| SCHEMBL2985359 | 0.80 | CES1 (0.54) | BLMKDM4EALDH1A1POLBRECQL | |
| SCHEMBL11990926 | 0.78 | SLC6A2 (0.55) | PDPK1ALDH1A1TDP1LMNAESR1 | |
| SCHEMBL27937876 | 0.78 | LMNA (0.45) | PDPK1BLMKDM4EALDH1A1ABL1 | |
| SCHEMBL670290 | 0.78 | KDM4E (0.58) | KDM4EPOLBGAAALPGRECQL | |
| Terephthalic Acid SCHEMBL27941219 | 0.78 | TSHR (0.54) | TDP1L3MBTL1LMNAPKMCES2 | |
| SCHEMBL8982949 | 0.77 | PDPK1 (0.57) | PDPK1BLMKDM4EALDH1A1ABL1 | |
| SCHEMBL18101799 | 0.77 | LMNA (0.51) | PDPK1BLMKDM4EALDH1A1ABL1 | |
| SCHEMBL29085758 | 0.77 | LMNA (0.51) | PDPK1BLMKDM4EALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | claimed |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | claimed |
| US-7427690-B2 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration | BIODERM RESEARCH (US) | 2008-09-23 | — | — | US | claimed |
| US-20070099886-A1 | Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration | BIODERM RESEARCH (US) | 2007-05-03 | — | — | US | claimed |
| US-20060074108-A1 | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition | BIODERM RESEARCH (US) | 2006-04-06 | — | — | US | claimed |
| US-20050271608-A1 | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives | GUPTA SHYAM K | 2005-12-08 | — | — | US | claimed |
| EP-1006405-B1 | Black and white thermographic recording material with improved image tone | AGFA GEVAERT (BE) | 2003-07-23 | — | — | EP | claimed |
| EP-0978760-B1 | Thermographic recording materials | AGFA GEVAERT (BE) | 2003-07-02 | — | — | EP | claimed |
| US-6313065-B1 | CONTAINING LIGHT-INSENSITIVE ORGANIC SILVER SALT, 1,2-DIHYDROXYBENZENE DERIVATIVE, POLYMER WITH ACTIVE HYDROGEN ATOMS WHICH HAVE, AT LEAST PARTIALLY, REACTED WITH A POLYISOCYANATE | AGFA-GEVAERT (BE) | 2001-11-06 | — | — | US | claimed |
| US-6211115-B1 | Reducing agents for use in thermographic recording materials | AGFA-GEVAERT (BE) | 2001-04-03 | — | — | US | claimed |
| EP-1006405-A1 | Black and white thermographic recording material with improved image tone | AGFA-GEVAERT N.V. (BE) | 2000-06-07 | — | — | EP | claimed |
| EP-0978760-A1 | Novel reducing agents for use in thermographic recording materials | AGFA-GEVAERT N.V. (BE) | 2000-02-09 | — | — | EP | claimed |
| US-8227426-B2 | Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care | ISLAND KINETICS INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | ISLAND KINETICS INC. (US) | 2011-03-10 | — | — | US | disclosed |
| US-7834210-B2 | Hair loss prevention by natural amino acid and peptide complexes | BIODERM RESEARCH (US) | 2010-11-16 | — | — | US | disclosed |
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-6313065-B1 | CONTAINING LIGHT-INSENSITIVE ORGANIC SILVER SALT, 1,2-DIHYDROXYBENZENE DERIVATIVE, POLYMER WITH ACTIVE HYDROGEN ATOMS WHICH HAVE, AT LEAST PARTIALLY, REACTED WITH A POLYISOCYANATE | AGFA-GEVAERT (BE) | 2001-11-06 | — | — | US | disclosed |
| US-6211115-B1 | Reducing agents for use in thermographic recording materials | AGFA-GEVAERT (BE) | 2001-04-03 | — | — | US | disclosed |
| EP-1006405-A1 | Black and white thermographic recording material with improved image tone | AGFA-GEVAERT N.V. (BE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0978760-A1 | Novel reducing agents for use in thermographic recording materials | AGFA-GEVAERT N.V. (BE) | 2000-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | GLA, LPO, PLOD3 | PDPK1 2318/4885BLM 3648/4885KDM4E 1594/4885 |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | PSMB1, PLOD3, CUTA | PDPK1 2086/4885BLM 2586/4885KDM4E 513/4885 |
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | PROC, COL1A1, CUTA | PDPK1 1471/4885BLM 3438/4885KDM4E 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.