Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179285 | 0.85 | UHRF1 (0.52) | UHRF1LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29508711 | 0.85 | UHRF1 (0.52) | UHRF1LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL84569 | 0.85 | UHRF1 (0.52) | UHRF1LMNAALDH1A1KDM4ECCR1 | |
| SCHEMBL278964 | 0.81 | LMNA (0.41) | LMNAALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29738718 | 0.81 | LMNA (0.41) | LMNAALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13153662 | 0.74 | CCR1 (0.68) | UHRF1LMNAALDH1A1KDM4ECCR1 | |
| SCHEMBL44068 | 0.72 | — | — | |
| SCHEMBL28381757 | 0.72 | UHRF1 (1.00) | UHRF1ALDH1A1KDM4ESMN1; SMN2CCR1 | |
| SCHEMBL29365333 | 0.72 | — | — | |
| SCHEMBL31032211 | 0.71 | UHRF1 (0.50) | UHRF1LMNAALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767671-B2 | STABILITY; HEAT RESISTANCE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-07-27 | — | — | US | disclosed |