SCHEMBL84569

SCHEMBL84569

Cc1cc(C(C)(C)C)ccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.52
KIF11 P52732 2/20 0.39
TSHR P16473 1/20 0.39
DYRK1A Q13627 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 3/20 0.37
LMNA P02545 1/20 0.37
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36
CCR8 P51685 1/20 0.36
POLB P06746 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
NOS3 P29474 2/20 0.34
NOS2 P35228 2/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7002997 0.85 UHRF1 (0.53) UHRF1KIF11TSHRDYRK1AALDH1A1
SCHEMBL16454307 0.82 UHRF1 (0.48) UHRF1DYRK1AALDH1A1CCR1CCR5
SCHEMBL2735689 0.82 UHRF1 (0.48) UHRF1TSHRDYRK1ACCR1CCR5
SCHEMBL30947587 0.82 UHRF1 (0.48) UHRF1DYRK1AALDH1A1CCR1CCR5
SCHEMBL10193125 0.82 UHRF1 (0.48) UHRF1DYRK1AALDH1A1CCR1CCR5
SCHEMBL25089926 0.82 UHRF1 (0.48) UHRF1DYRK1AKDM4ECCR1CCR5
SCHEMBL19454592 0.82 UHRF1 (0.48) UHRF1DYRK1AKDM4EKMT2AMEN1
SCHEMBL19413079 0.80 UHRF1 (0.46) UHRF1DYRK1AALDH1A1TDP1LMNA
SCHEMBL23639388 0.80 ADRA2A (0.43) UHRF1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL29497390 0.79 NOS3 (0.57) UHRF1ALDH1A1NOS3NOS2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172878-B1 Non-aqueous electrolytic solution and secondary battery containing same MITSUBISHI CHEM CORP (JP) 2011-06-22 EP claimed
US-6767671-B2 STABILITY; HEAT RESISTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 2004-07-27 US claimed
US-20020025477-A1 Non-aqueous electrolytic solution and secondary battery containing same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-02-28 US claimed
EP-1172878-A2 Non-aqueous electrolytic solution and secondary battery containing same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-16 EP claimed
WO-2025062334-A1 4-((5-(3-(4-(PYRIDIN-2-YL)CYCLOPENTYL)-1 H-PYRAZOL-3-YL)AMINO)-BENZENESULFONAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER BEIGENE SWITZERLAND GMBH (CH) 2025-03-27 WO disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12043620-B2 Benzazole compounds and methods for making and using the compounds RIGEL PHARMACEUTICALS, INC. (US) 2024-07-23 US disclosed
US-12043620-B2 Benzazole compounds and methods for making and using the compounds RIGEL PHARMACEUTICALS, INC. (US) 2024-07-23 US disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 US disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 US disclosed
CN-118290328-A Hydrocarbon pyridine and preparation method thereof 北京师范大学 2024-07-05 CN disclosed
US-20240217963-A1 RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2024-07-04 US disclosed
EP-0710688-A1 HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-05-08 EP disclosed
US-5200488-A POLYORGANOSILOXANE HAVING A QUATERNARY SALT AT ITS ONE TERMINAL AND PERCUTANEOUS ABSORPTION-PROMOTING AGENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-04-06 US disclosed
EP-0484857-A2 Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-05-13 EP disclosed
US-4871848-A OIL, GAS WELLS CORROSION INHIBITORS THE DOW CHEMICAL COMPANY (US) 1989-10-03 US disclosed
US-4740320-A REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE THE DOW CHEMICAL COMPANY (US) 1988-04-26 US disclosed
US-4725373-A CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US disclosed
US-4724003-A Asphalt compositions containing anti-stripping additives prepared from hydrocarbyl substituted nitrogen-containing aromatic heterocyclic compounds, aldehydes or ketones and amines THE DOW CHEMICAL COMPANY (US) 1988-02-09 US disclosed
US-4676834-A Novel compositions prepared from methyl substituted nitrogen-containing aromatic heterocyclic compounds and an aldehyde or ketone THE DOW CHEMICAL COMPANY (US) 1987-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043620-B2 Benzazole compounds and methods for making and using the compounds IRAK3, IRAK1, IRAK2 UHRF1 2960/4885KIF11 3822/4885TSHR 4160/4885
US-12043613-B2 Inhibitors of SARM1 SARM1, SMN1; SMN2, SARNP UHRF1 1680/4885KIF11 1631/4885TSHR 3994/4885
US-12030853-B2 MASP-2 inhibitors and methods of use MASP2, METAP2, SPINT2 UHRF1 2048/4885KIF11 3394/4885TSHR 3550/4885
US-20240217963-A1 RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS, PREPARATIONS, AND USES THEREOF RIPK1, RIPK2, RIPK4 UHRF1 864/4885KIF11 4319/4885TSHR 1967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.