SCHEMBL278964

SCHEMBL278964

CC(C)(C)c1ccnc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KIF11 P52732 2/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.38
PRKCI P41743 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29738718 1.00 LMNA (0.41) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL12553830 0.85 KIF11 (0.40) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL91323 0.85 LOXL2 (0.48) KIF11ALDH1A1HSD17B10HPGDALOX15
SCHEMBL19522383 0.85 SCN10A (0.39) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL14868350 0.85 ALDH1A1 (0.39) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL24132435 0.85 KIF11 (0.36) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL18401547 0.85 KIF11 (0.36) LMNASMN1; SMN2NPC1RAB9AKIF11
SCHEMBL14349599 0.85 NOS3 (0.39) LMNASMN1; SMN2NPC1RAB9ATSHR
SCHEMBL12553833 0.85 NOS3 (0.39) LMNASMN1; SMN2NPC1RAB9AHTT
SCHEMBL2609325 0.85 NOS3 (0.53) LMNASMN1; SMN2NPC1RAB9AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504803-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES Promerus, LLC (US) 2025-02-12 EP claimed
WO-2023196366-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-12 WO claimed
US-20230312775-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-05 US claimed
CN-112094300-A Dicyano tetra-tert-butyl pyridine ruthenium metal organic compound, preparation method and application thereof 荆楚理工学院 2020-12-18 CN claimed
US-9415354-B2 Organopalladium compounds as polymerization catalysts PROMERUS, LLC (US) 2016-08-16 US claimed
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-18 US claimed
US-8697820-B2 Process for preparing high-reactivity isobutene homo- or copolymers BASF SE (DE) 2014-04-15 US claimed
EP-0797594-A1 INITIATION VIA HALOBORATION IN LIVING CATIONIC POLYMERIZATION UNIVERSITY OF MASSACHUSETTS LOWELL (US) 1997-10-01 EP claimed
WO-1995017436-A1 INITIATION VIA HALOBORATION IN LIVING CATIONIC POLYMERIZATION UNIVERSITY OF MASSACHUSETTS LOWELL (US) 1995-06-29 WO claimed
EP-4638569-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITIATED MASS POLYMERIZATION Promerus, LLC (US) 2025-10-29 EP disclosed
EP-4612126-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M Innovative Properties Company (US) 2025-09-10 EP disclosed
US-20250177927-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION PROMERUS, LLC (US) 2025-06-05 US disclosed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US disclosed
US-12251668-B2 Supported membranes by thermal and UV initiated mass polymerization PROMERUS, LLC (US) 2025-03-18 US disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
CN-1290275-A Catalyst and process for polymerization of cycloolefin GOODRICH CO B F (US) 2001-04-04 CN disclosed
EP-1034196-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-09-13 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS MVD, DDT, CDV3 LMNA 4587/4885SMN1; SMN2 3119/4885NPC1 3371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.