Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006801 | 0.94 | MAPK14 (0.54) | MAPK14ALOX5 | |
| SCHEMBL7006817 | 0.90 | SNRNP200 (0.45) | MAPK14KDM4CALOX5CYP3A4 | |
| SCHEMBL7006120 | 0.87 | CYP3A4 (0.43) | MAPK14ALOX5CYP3A4CYP19A1CYP11B1 | |
| SCHEMBL7005838 | 0.84 | TDP1 (0.42) | MAPK14ALOX5 | |
| SCHEMBL7004499 | 0.83 | MCHR1 (0.47) | MAPK14ALOX5 | |
| SCHEMBL7001976 | 0.79 | MCHR1 (0.47) | MAPK14ALOX5HTR6 | |
| SCHEMBL7006729 | 0.79 | ALOX5 (0.48) | MAPK14ALOX5 | |
| SCHEMBL7009665 | 0.78 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9194734 | 0.78 | ROCK1 (0.54) | MAPK14KDM4CALOX5CYP3A4HTR6 | |
| SCHEMBL7005488 | 0.75 | HPGD (0.47) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |