Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006801 | 0.88 | MAPK14 (0.54) | ALOX5HTR7MAPK14MAOBMAOA | |
| SCHEMBL7001976 | 0.87 | MCHR1 (0.47) | MCHR1ALOX5HTR7MAPK14MAOB | |
| SCHEMBL7006729 | 0.85 | ALOX5 (0.48) | ALOX5HTR7MAPK14HRH3MAOB | |
| SCHEMBL7003158 | 0.83 | MAPK14 (0.48) | ALOX5MAPK14 | |
| SCHEMBL7006120 | 0.82 | CYP3A4 (0.43) | ALOX5HTR7MAPK14MAOBMAOA | |
| SCHEMBL7009665 | 0.81 | ALOX5 (0.47) | MCHR1ALOX5MAOBMAOAMEN1 | |
| SCHEMBL7006817 | 0.81 | SNRNP200 (0.45) | ALOX5MAPK14 | |
| SCHEMBL7005838 | 0.81 | TDP1 (0.42) | ALOX5HTR7MAPK14MAOBMAOA | |
| SCHEMBL7002364 | 0.77 | NPC1 (0.47) | MCHR1MEN1NPC1KMT2ARAB9A | |
| SCHEMBL7003213 | 0.76 | NSD2 (0.50) | ALOX5MAPK14MAOBMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |