Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600253 | 0.78 | P2RX7 (0.52) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL31306809 | 0.78 | P2RX7 (0.52) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL667384 | 0.78 | NFKB1 (0.51) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL380569 | 0.77 | JUN (0.45) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL6418676 | 0.74 | JUN (0.51) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL4155438 | 0.74 | JUN (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL30553734 | 0.74 | JUN (0.59) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL6983154 | 0.74 | JUN (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL29988880 | 0.74 | NFKB1 (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL20152022 | 0.74 | JUN (0.48) | JUNNFKB1NFKB2RELAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268443-A1 | 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE | SmithKline Beecham p.l.c. (GB) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074788-A1 | 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE | SMITHKLINE BEECHAM PLC (GB) | 2001-10-11 | — | — | WO | disclosed |