Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.83 |
| ▸ | RAB9A | P51151 | 12/20 | 0.83 |
| ▸ | NPC1 | O15118 | 11/20 | 0.83 |
| ▸ | MAPT | P10636 | 10/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.83 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.83 |
| ▸ | RELA | Q04206 | 4/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746267 | 0.91 | KDM4E (1.00) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL7004578 | 0.91 | KDM4E (1.00) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL7005467 | 0.76 | MAPT (0.50) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL1304848 | 0.76 | MAOA (0.57) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL34467584 | 0.76 | NPC1 (0.63) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL240431 | 0.76 | NPC1 (0.63) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL12112870 | 0.75 | RAB9A (0.80) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL2220158 | 0.74 | NPC1 (0.61) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL4337601 | 0.74 | NPC1 (0.61) | SMN1; SMN2RAB9ANPC1MAPTKDM4E | |
| SCHEMBL17449881 | 0.74 | RAB9A (0.62) | SMN1; SMN2RAB9ANPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |