SCHEMBL7004070

SCHEMBL7004070

Cc1c(O[Si](C)(C)C(C)(C)C)ccc2c[c]ccc12

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA9 Q16790 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200102 0.81 KDM4E (0.32) CA12CA1CA9
SCHEMBL5375380 0.76 PREP (0.33) CA12CA1CA9
SCHEMBL9164412 0.76 MAPT (0.36)
SCHEMBL1414983 0.75 LMNA (0.42) CA12CA1CA9
SCHEMBL1987012 0.74 CA12 (0.32) CA12CA1CA9
SCHEMBL7197682 0.72 KDM4E (0.32) CA12CA1CA9
SCHEMBL4027512 0.71 CA12 (0.52) CA12CA1CA9
SCHEMBL7197552 0.71 KDM4E (0.33) CA12CA1CA9
SCHEMBL1206219 0.70 ALDH1A1 (0.37) CA12CA1CA9
SCHEMBL6199747 0.70 ALOX5AP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1344777-A1 IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2003-09-17 EP disclosed