Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011260 | 0.82 | NPSR1 (0.40) | POLBMAPTALDH1A1LMNASLC1A2 | |
| Hydrochloric Acid SCHEMBL7005188 | 0.81 | MAPT (0.36) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL400161 | 0.81 | POLB (0.70) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7007204 | 0.79 | HSD17B10 (0.44) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL27289520 | 0.79 | POLB (0.68) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9054906 | 0.78 | MAPT (0.37) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27141812 | 0.76 | HSD17B10 (0.50) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7009778 | 0.76 | MAPK1 (0.43) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19403521 | 0.75 | RAB9A (0.67) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9275547 | 0.74 | RAB9A (0.66) | MAPTNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |