Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747135 | 0.93 | MAPT (0.55) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL30443578 | 0.84 | MAOB (0.63) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL2965418 | 0.84 | MAOB (0.63) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL25920598 | 0.83 | MAPT (0.62) | MAPTMEN1KMT2ALMNAAR | |
| SCHEMBL25920602 | 0.82 | MAOB (0.64) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL3402348 | 0.81 | CHRNB2 (0.56) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL16178929 | 0.80 | CHRNB2 (0.64) | CHRNB2CHRNA4MAPTLMNAMAOB | |
| Hydroquinone SCHEMBL29014236 | 0.80 | MAOB (0.61) | MAPTMEN1KMT2ALMNAAR | |
| SCHEMBL20303777 | 0.80 | CHRNB2 (0.55) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL6057213 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309551-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014273-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-21 | — | — | WO | disclosed |