Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.64 |
| ▸ | MMP13 | P45452 | 20/20 | 0.64 |
| ▸ | MMP1 | P03956 | 19/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 18/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7008500 | 0.89 | MMP9 (0.78) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7012171 | 0.86 | MMP9 (0.69) | MMP9MMP13MMP1ADAM17 | |
| Hydroxyamine SCHEMBL7538525 | 0.85 | MMP9 (0.67) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7010199 | 0.83 | MMP9 (0.69) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7013016 | 0.82 | MMP9 (0.79) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7012090 | 0.82 | MMP13 (0.79) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7008539 | 0.82 | MMP13 (0.77) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7006168 | 0.82 | MMP13 (0.79) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7011410 | 0.82 | MMP13 (0.79) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7012033 | 0.82 | MMP9 (0.57) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021413-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | WYETH CORP (US) | 2003-06-11 | — | — | EP | claimed |