Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.67 |
| ▸ | MMP13 | P45452 | 20/20 | 0.67 |
| ▸ | MMP1 | P03956 | 19/20 | 0.67 |
| ▸ | ADAM17 | P78536 | 18/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012171 | 0.98 | MMP9 (0.69) | MMP9MMP13MMP1ADAM17 | |
| Hydroxyamine SCHEMBL7473572 | 0.89 | MMP9 (0.83) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6289415 | 0.88 | MMP9 (0.86) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7006104 | 0.87 | MMP9 (0.68) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7004398 | 0.85 | MMP9 (0.64) | MMP9MMP13MMP1ADAM17 | |
| Hydroxyamine SCHEMBL7474026 | 0.81 | MMP9 (0.59) | MMP9MMP13MMP1ADAM17 | |
| Hydroxyamine SCHEMBL7539030 | 0.81 | MMP13 (0.83) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6290585 | 0.81 | MMP1 (0.75) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7479103 | 0.80 | MMP1 (0.74) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6293930 | 0.80 | MMP9 (0.80) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016514-A1 | ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | claimed |