Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004490 | 0.89 | GPBAR1 (0.64) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7007754 | 0.88 | NPC1 (0.54) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7004665 | 0.85 | NPC1 (0.48) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL29746123 | 0.83 | RAB9A (0.69) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL6851588 | 0.83 | RAB9A (0.69) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL10665251 | 0.83 | CYP3A4 (0.56) | PDE10ASMN1; SMN2GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL3631400 | 0.82 | FGFR1 (0.54) | SMN1; SMN2KDM4EALDH1A1RAB9ATP53 | |
| SCHEMBL6858239 | 0.82 | RAB9A (0.67) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8775301 | 0.81 | TP53 (0.46) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL28180362 | 0.81 | MAPT (0.55) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |