Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004489 | 0.85 | PDE10A (0.52) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7004490 | 0.82 | GPBAR1 (0.64) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6851588 | 0.80 | RAB9A (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29746123 | 0.80 | RAB9A (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10665251 | 0.80 | CYP3A4 (0.56) | SMN1; SMN2GPBAR1CYSLTR1CYSLTR2CYP3A4 | |
| SCHEMBL6858239 | 0.79 | RAB9A (0.67) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12251030 | 0.77 | BACE1 (0.50) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL7005638 | 0.76 | MAP4K4 (0.56) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12250931 | 0.76 | GGPS1 (0.56) | — | |
| SCHEMBL17449881 | 0.75 | RAB9A (0.62) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |