SCHEMBL7004760

SCHEMBL7004760

Cc1c(-c2ccc3ccccc3n2)cc(N(C)C)cc1N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.42
AR P10275 7/20 0.41
RAB9A P51151 7/20 0.40
NPC1 O15118 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
ALDH1A1 P00352 3/20 0.39
PTK2B Q14289 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CNR2 P34972 2/20 0.39
CYP1A2 P05177 2/20 0.39
SLC2A1 P11166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004662 0.82 AR (0.41) ARRAB9ANPC1MEN1KMT2A
SCHEMBL7004432 0.81 AR (0.40) ARRAB9ANPC1MEN1KMT2A
SCHEMBL7004485 0.81 AR (0.40) ARRAB9ANPC1MEN1KMT2A
SCHEMBL7004495 0.79 AR (0.50) NCF1ARRAB9ANPC1MEN1
SCHEMBL7005082 0.79 AR (0.39) ARRAB9ANPC1MEN1KMT2A
SCHEMBL6482442 0.77 NCF1 (0.52) NCF1ARRAB9ANPC1MEN1
SCHEMBL7004636 0.75 RAB9A (0.51) NCF1ARRAB9ANPC1MEN1
SCHEMBL16310381 0.71 AR (0.59) ARRAB9ANPC1MEN1KMT2A
SCHEMBL62397 0.70 RAB9A (0.61) NCF1ARRAB9ANPC1MEN1
SCHEMBL7004623 0.69 S100A4 (0.42) NCF1RAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012064499-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2012-05-18 WO disclosed