Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006876 | 0.87 | ADRB3 (0.44) | KDM4ENPC1ALDH1A1RAB9APPARD | |
| SCHEMBL7008000 | 0.83 | TRPV1 (0.49) | S1PR1S1PR3TRPV1 | |
| SCHEMBL8553275 | 0.83 | GRM5 (0.41) | S1PR1S1PR3TRPV1TOP1 | |
| SCHEMBL7009043 | 0.82 | S1PR1 (0.53) | S1PR1S1PR3TRPV1KDM4ENPC1 | |
| SCHEMBL7009823 | 0.81 | S1PR1 (0.48) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL3559671 | 0.81 | S1PR1 (0.55) | S1PR1S1PR3SYKTOP1RAD51 | |
| SCHEMBL8724649 | 0.81 | KDM4E (0.49) | TRPV1KDM4EALDH1A1RAB9ACYP1A2 | |
| SCHEMBL7866159 | 0.80 | S1PR1 (0.44) | S1PR1S1PR3TRPV1TOP1KDM4E | |
| SCHEMBL7006071 | 0.79 | S1PR1 (0.48) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL5252670 | 0.78 | S1PR1 (0.52) | S1PR1S1PR3TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | claimed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | claimed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| US-6008161-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824624-A | HERBICIDES WITH CARRIERS OR SURFACTANTS | AMERICAN CYANAMID COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | disclosed |