Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009043 | 0.92 | S1PR1 (0.53) | S1PR1S1PR3CYP1A2CYP2C9TRPV1 | |
| SCHEMBL7006071 | 0.88 | S1PR1 (0.48) | S1PR1S1PR3CYP1A2CYP2C9TRPV1 | |
| SCHEMBL7006595 | 0.87 | MAPK1 (0.46) | MAPK1CYP1A2CYP2C9MAPTL3MBTL1 | |
| SCHEMBL5252670 | 0.85 | S1PR1 (0.52) | S1PR1S1PR3FFAR4TRPV1SCN9A | |
| SCHEMBL7007490 | 0.85 | S1PR1 (0.46) | S1PR1S1PR3MAPK1TRPV1FPR2 | |
| SCHEMBL8722892 | 0.82 | MAPK1 (0.43) | S1PR1MAPK1CYP1A2CYP2C9MAPT | |
| SCHEMBL7004813 | 0.81 | S1PR1 (0.43) | S1PR1S1PR3CYP1A2CYP2C9TRPV1 | |
| SCHEMBL7006435 | 0.81 | L3MBTL1 (0.58) | MAPK1CYP1A2CYP2C9MAPTL3MBTL1 | |
| SCHEMBL7007712 | 0.81 | S1PR1 (0.47) | S1PR1S1PR3CYP1A2CYP2C9MAPT | |
| SCHEMBL7011308 | 0.78 | S1PR1 (0.47) | S1PR1S1PR3CYP1A2CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| US-6008161-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824624-A | HERBICIDES WITH CARRIERS OR SURFACTANTS | AMERICAN CYANAMID COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | disclosed |