Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006071 | 0.94 | S1PR1 (0.48) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL7009823 | 0.92 | S1PR1 (0.48) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL5252670 | 0.91 | S1PR1 (0.52) | S1PR1S1PR3TRPV1SCN9ATHRB | |
| SCHEMBL7007490 | 0.89 | S1PR1 (0.46) | S1PR1S1PR3TRPV1FPR2SCN9A | |
| SCHEMBL7004813 | 0.82 | S1PR1 (0.43) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL7008000 | 0.81 | TRPV1 (0.49) | S1PR1S1PR3TRPV1SCN9A | |
| SCHEMBL7007712 | 0.81 | S1PR1 (0.47) | S1PR1S1PR3TRPV1CYP1A2CYP2C9 | |
| SCHEMBL30864860 | 0.80 | KCNH2 (0.46) | S1PR1S1PR3SCN9ATHRBKCNH2 | |
| SCHEMBL27314076 | 0.80 | KCNH2 (0.46) | S1PR1S1PR3SCN9ATHRBKCNH2 | |
| SCHEMBL8553275 | 0.79 | GRM5 (0.41) | S1PR1S1PR3TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0823431-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1998-02-11 | — | — | EP | disclosed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | disclosed |