Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549067 | 0.89 | CTSS (0.45) | GRM5CTSSCTSKKCNH2 | |
| SCHEMBL8553832 | 0.88 | TRPV1 (0.43) | TRPV1KIF11CTSSCTSKTOP1 | |
| SCHEMBL8552904 | 0.85 | TRPV1 (0.39) | TRPV1KIF11CTSSCTSKTOP1 | |
| SCHEMBL7004813 | 0.83 | S1PR1 (0.43) | S1PR1S1PR3TRPV1TOP1 | |
| SCHEMBL8552758 | 0.82 | KIF11 (0.42) | TRPV1KIF11CTSSCTSKKCNH2 | |
| SCHEMBL8548872 | 0.82 | POLB (0.43) | TRPV1KIF11CTSSCTSK | |
| SCHEMBL7008000 | 0.81 | TRPV1 (0.49) | S1PR1S1PR3TRPV1 | |
| SCHEMBL8549675 | 0.80 | ADORA1 (0.46) | TRPV1KIF11CTSSCTSKKCNH2 | |
| SCHEMBL8471818 | 0.79 | PSD (0.41) | CTSSPSD | |
| SCHEMBL7009043 | 0.79 | S1PR1 (0.53) | S1PR1S1PR3TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |