Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010966 | 0.73 | ADRA1D (0.39) | — | |
| SCHEMBL29951981 | 0.68 | USP2 (0.40) | LMNAALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL845035 | 0.68 | — | — | |
| SCHEMBL29026891 | 0.67 | SMN1; SMN2 (0.45) | LMNAALDH1A1 | |
| SCHEMBL7014325 | 0.67 | GPR35 (0.33) | — | |
| SCHEMBL27972246 | 0.66 | ERN1 (0.31) | ERN1PRKDC | |
| SCHEMBL7005875 | 0.64 | — | — | |
| SCHEMBL17428932 | 0.63 | CYP2A6 (0.36) | LMNAALDH1A1 | |
| SCHEMBL5803353 | 0.63 | MGLL (0.32) | ALDH1A1 | |
| SCHEMBL13510846 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690863-B1 | TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS | ABBOTT LAB (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5597832-A | TREATMENT OF NEUROLOGICAL, PSYCHOLOGICAL, CARDIOVASCULAR DISORDERS, AND SUBSTANCE ABUSE, BEHAVIOR DISORDERS, COGNITIVE IMPAIRMENT AND ATTENTION DEFICIT DISORDER | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |