Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993174 | 0.89 | PTGES (0.56) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL7000442 | 0.89 | PTGES (0.56) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL7002206 | 0.87 | PTGS2 (0.55) | ALOX5KMT2APTGS1PTGS2 | |
| SCHEMBL7001656 | 0.82 | KMT2A (0.52) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL6475809 | 0.81 | KMT2A (0.53) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL7003600 | 0.77 | PTGES (0.56) | ALOX5PTGESPTGS1PTGS2 | |
| SCHEMBL7003381 | 0.77 | PTGES (0.56) | ALOX5PTGESPTGS1PTGS2 | |
| SCHEMBL7003945 | 0.75 | PTGS2 (0.44) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL7003650 | 0.75 | PTGS2 (0.44) | ALOX5KMT2AMEN1PTGESPTGS1 | |
| SCHEMBL6475197 | 0.75 | KMT2A (0.70) | ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246825-B1 | FUSED PYRROLE COMPOUNDS, PHARMACEUTICAL AGENTS CONTAINING THE SAME, AND THE USE THEREOF | MERCKLE GMBH (DE) | 2003-12-17 | — | — | EP | disclosed |