Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.74 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.74 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238675 | 1.00 | MTNR1B (0.74) | MTNR1BMTNR1AKDM1AMAOAGLA | |
| SCHEMBL7009066 | 0.92 | MTNR1A (0.76) | MTNR1BMTNR1AKDM1AMAOA | |
| SCHEMBL7237873 | 0.92 | MTNR1A (0.76) | MTNR1BMTNR1AKDM1AMAOA | |
| SCHEMBL7228835 | 0.86 | MTNR1A (0.76) | MTNR1BMTNR1A | |
| SCHEMBL7010173 | 0.86 | MTNR1A (0.76) | MTNR1BMTNR1A | |
| SCHEMBL7009286 | 0.85 | MTNR1A (1.00) | MTNR1BMTNR1AKDM1AMAOA | |
| SCHEMBL7238295 | 0.85 | MTNR1A (1.00) | MTNR1BMTNR1AKDM1AMAOA | |
| SCHEMBL7005998 | 0.82 | MTNR1B (0.57) | MTNR1BMTNR1AGLA | |
| SCHEMBL7012027 | 0.82 | MTNR1B (0.57) | MTNR1BMTNR1AGLA | |
| SCHEMBL7230327 | 0.78 | MTNR1A (0.77) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | claimed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | claimed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | claimed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |