Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811132 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL7010444 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL10516112 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL7004953 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL7506686 | 0.81 | KMT2A (0.39) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL2915243 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL7005401 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL2901699 | 0.78 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL966496 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL30181119 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EMEN1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |